Waldenstrom's Macroglobulinemia
Biological Therapy Treatment For Waldenstrom’s Macroglobulinemia

Biological Therapy Treatment

Biological therapy is a treatment in which the body's natural portion immune system is used to treat Waldenstrom’s macroglobulinemia. Biological therapy is also known as immunotherapy, biotherapy, or biological response modifier therapy. Biological therapy helps the body to establish its immune system to fight against the cancerous cells, infection and diseases. Biological therapy helps in controlling side effects occurring due to other therapies treatment.

Biological therapy normally works on:

  • Increasing the strength of immune cells.
  • Changing the mutation of cancer cells, effectively meaning that they behave like common cells in body.
  • Helping immune cells to locate cancer cells so that they can be cured easily. Also, preventing common cells getting converted into cancerous cells.

There are various types of biological therapies. They are differentiated on the basis of type of BRMs (Biological Response Modifiers) used for treating Waldenstrom’s Macroglobulinemia. Some widely used types are Non Specific Immunomodulating Agents; Inferons, Interleukins and Monoclonal antibodies. Anti-angiogenesis Is also a popular type used in advance stages of cancer, which uses a specific technique. It stops the formation of new blood cells in the tumour part of the body. Without supply of blood cells they end up getting diminished. Also one important and most recently developed type is vaccine therapy which is still at experimentation stage. Like in other diseases a vaccine is given to the patient to stop the cancer cells from spreading. Unlike other vaccines this is given after Waldenstrom’s Macroglobulinemia is detected.

The advantage of biological therapy is that it is very specific and hence there is less damage done to normal cells. It also reduces the rate of increase of the tumour. Moreover it increases the patient’s immunity so as to prevent damage on the normal cells.

Biological therapy, although one of safest ways of treating cancer, has some side effects. Most common are mild fever, chills, nausea, vomiting and fatigue. The level of side effects depends on medical profile of the person being treated. It is always advisable for the patient to discuss this aspect with the medical practitioner before starting the treatment.

Difference To Chemotherapy Treatment

Both therapies are cancer fighters. In chemotherapy, cancerous cells are directly attacked which may lead to side effects. In biological therapy, the patients immune system is targeted to fight against the cancerous cells. Biological therapy may stop or slow down the growth of the cancer cells. It also makes the patient’s immune system destroy or get rid of the cancer cells and stops the cancer cells from spreading to other parts of the body. Clinical trials are being carried out by doctors for various biological therapies to make it more effective. Looking at this it can be concluded that this would be an important way in mankind’s fight against cancer.